All Things Skin

The Science of Telomeres: Unlocking Cellular Age Reversal

Dr. Missy Clifton, MD, FAAD, FASDS Season 4 Episode 4

Dive into the fascinating world of cellular aging with Sebastian Conti, Sales Director at TA Sciences, as we explore the science behind telomeres—those tiny protective caps at the ends of your chromosomes that may hold the key to biological aging.

Sebastian breaks down complex concepts into accessible insights, explaining how telomeres naturally shorten as we age and how this process connects directly to age-related diseases like cardiovascular issues, Alzheimer's, and cancer. What separates TA-65 from other supplements is its impressive scientific backing—twelve published clinical studies, including five double-blind trials—demonstrating its ability to activate telomerase and potentially lengthen telomeres.

The conversation takes us through the practical benefits users experience: improved cognitive function, enhanced recovery after exercise, stronger immune response, and sometimes even improved eyesight in cases of early macular degeneration. Sebastian shares his personal journey with the supplement, noting improved mental clarity and faster physical recovery after about seven months of consistent use.

We also explore who might benefit most from telomerase activation, from high-performance athletes looking for better recovery to adults over 50 experiencing the more noticeable effects of aging. The supplement's ability to reduce senescent cell load—particularly in CMV-positive individuals—and replenish naive T-cell reserves makes it a compelling option for immune health as well.

Whether you're already deep into your wellness journey or just beginning to explore anti-aging interventions, this episode offers valuable insights into addressing aging at its most fundamental level—your DNA. Ready to explore what telomere science could mean for your longevity? Listen now and discover how cellular rejuvenation might change your approach to aging.

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Speaker 1:

Hello listeners and thank you for joining us for another episode of All Things Skin, and today I have Sebastian Conte, who is the sales director at TA Sciences, joining me today. Sebastian, welcome, Thank you for being here. Thanks for having me. Dr Clifton, Absolutely so. Tell us a little bit about TA Sciences and what you guys have going on over there.

Speaker 2:

Yeah, so TA Sciences. The TA stands for Telomerase Activation Sciences. We specialize in products that you can take to activate telomerase and lengthen telomeres. Really, what we have is a flagship product that's an oral supplement and you're familiar with it, obviously, and we're going to talk about that.

Speaker 1:

Yeah, let's start first of all with what's a telomere, because a lot of our listeners may not actually know what is a telomere.

Speaker 2:

Of course. So if any of you ever can go back to your eighth grade biology class and you can remember the twisted ladder that was the double helix, the double-stranded DNA at the end, either end of that double-stranded DNA is two little tails and those are the end caps of your chromosome. Those are the telomeres, and the real, simple role that I can say that they play in the process of your cells is they help protect the cell through cellular division and as we age our cells have to divide and we want them to divide cleanly. We don't want to have a lot of DNA breakage or lack of recognition of proper DNA structure. So the telomeres help protect that. Now, as we get older and they lose their length, as they sacrifice themselves over the course of time in cellular replication, they don't grow back. They don't grow back on their own. Typically it's very difficult for them to do that.

Speaker 2:

Our product provides the support that your cells need to promote telomere regrowths and it does it transiently, and transiently means it's very mild. It only has a certain amount of time that it's in your bloodstream to help promote that growth. So it's safe and effective. We've got many years of published clinical data behind it now and we've got GRAS certification with the FDA as well. That does not mean we're an FDA approved product. I want to be clear on that. But yeah, so telomeres, are they important? Maybe looking at telomere age is important as well, and it gives them a general idea of where they are in regards to their biological versus chronological age, if you want to elaborate on that for some folks, yeah, so you know our biological age is actually, you know how old our cells really really are.

Speaker 1:

you know, as opposed to, how old they are by year. So we can, our biologic age can can be a little bit different from our chronological age.

Speaker 2:

And so how do you guys measure that, sebastian? So we don't, we don't actually provide the test and measured it, but what? What we do is when we recommend companies that do, they take a simple blood sample and you get it from, and they you get it from. Your white blood cells is what they look at. So they're measuring leukocytes and granulocytes. Anyways, what that does is it's going to help you determine where you are in compared to your sex and age amongst other cohorts that are similar to that sex and age group, and so obviously we want to be in the higher percentile. You know, if you're in the 80th, 90th percentile of telomere length for your age. Let's just say you're a 50 year old male and you're up there, you're probably looking very good, you've been taking care of yourself or you could have possibly inherited longer telomeres.

Speaker 2:

There's a whole bunch of dynamics between how health and telomeres are associated. We can say that from looking at clinical data and studies that this is non-product, relevant, that there is a direct correlation to a high percentage of short telomeres, which is what we do not want. Remember, we don't want a lot of short telomeres directly associated to onset of early age diseases or aging diseases in general and the big ones that we are familiar with, especially the biggest killers in society in the US at least, cardiovascular Alzheimer's and cancer, and there's quite a bit of data backing up that. If you look at, one common thing between all individuals that are associated with those disease types they all have a high percentage of short-tailed nurse.

Speaker 1:

Well, okay, that's fascinating. I didn't realize that that was the case. That makes perfect sense. So what can we do as consumers? Certainly? Besides, take your product. What can you do to lengthen your telomeres or to activate telomerase, naturally? Are there ways to do that?

Speaker 2:

There's ways to certainly preserve it, there's still the ways to potentially activate it. You know there's a, if you've people are familiar with hyperbarics, hyperbaric oxygen chamber therapy you can certainly help preserve telomere length and have some benefits from that, especially if you're doing it in a continuous fashion. Now, that's mainly. You can go in a whole rabbit hole in regards to acute, non-acute settings with hyperbarics. But mild hyperbaric therapies for non-acute situations I think are ideal. That's one way.

Speaker 2:

Another way is, if you hear people talking about practicing yoga, really anything that you can do to reduce stress, you know in general I will say that if you can help mitigate onset or production in higher oxidative stress levels, so if you can kind of curb oxidative stress, you can really help reduce the telomere degradation rate in your body, because oxidative stress plays a huge role in telomere degradation, as it is. One other thing I would say too that to look at and this is simple for a lot of practitioners our clients do you don't always have to measure telomeres per se and say, oh, we all know that we're aging, we all know that our cells are dividing and telomeres are shortening over time. That's just a. It's sort of unequivocally you know it's happening right.

Speaker 1:

It's a fact, a fact of aging.

Speaker 2:

Another thing you can look at is what is our senescent cell load, and you can actually measure that, and one of the ways to do that is actually looking at somebody whether or not they're CMV positive.

Speaker 2:

Now, cmv in this case stands for cytomegalovirus. It's not a well-known thing. Maybe it is more amongst the practitioner world, but not necessarily amongst just the standard population In the US. The statistic is that it's literally a coin toss after the age of 40 that you're CMV positive. It's asymptomatic, it's a form of herpes, but it's not the herpes that we all think of when we hear herpes. You're not going to get the sores on your lip and things like that. It's something that actually is just directly correlated to immune and what that does is it sort of immunocompromises you as you get older. Now this causes a much higher senescence cell load buildup. That's why, one of the things you can do as a practitioner or even as an individual, you can go into any lab camp or Quest lab in the US and you can ask them specifically for what's called an IgG titer, t-i-t-e-r, specifically looking for CMV. If you're CMV positive, don't panic, it's not a big deal. A lot of people are. There's a lot of things you can do. You're mainly just doing health maintenance, ta65, our product directly.

Speaker 2:

And now, mind you, I want to put a note on this we're not intended to treat or cure anything. This doesn't do that. It's a supplement. But in our published clinical data double-blinded human trial data actually we are proven to help reduce that senescent cell load significantly in all patients and, really important, in the CMV individuals. So we really make an impact there and it helps with that cellular inflammation reduction that takes place. A lot of companies talk about senescence and reducing it. A lot of them do a great job. What we've done is taken it a step further by actually measuring specific senescent cell markers and doing double-blinded human trial data with our product directly to show the results, and a lot of people cannot provide that information for you. So that's one thing we've just been proving. I know that you and I have talked about this in the past. This is why you trust what we have to offer.

Speaker 1:

Right, yeah, so many things in the supplement market. It feels like the wild wild west a little bit, you know, and in the United States there doesn't, there's not a lot of regulation around supplements, so I that was one thing that really attracted me to to your company is that you guys are really doing the science and it's actually a really reputable company. Tell us a little bit more about the company and how long you guys have been around and kind of the history of how you came to the space.

Speaker 2:

Yeah, sure thing. So I don't know if you heard the part about so. We're a great scientific company and probably not the best at marketing, but we put a lot of our focus into that. But I'll tell you a little history about the molecule. We didn't create it or discover it. Geron Corporation is a large pharmaceutical R&D company and in the 90s there was a lot of research going into developing an anti-aging drug. Believe it or not, they were kind of hedging right and they discovered TA65. And they actually named the molecule. We never changed the name of it, uh, and in research data they actually this molecule has already made it to face three drug trials.

Speaker 2:

Okay, it's already had a lot of proven uh, um, you know that it works, that all the things that all the benefits of it are there, uh, and they abandoned the project and went to another and went to another drug application that they pursued because they realized the FDA wasn't going to approve aging as a condition or disease. Really, for a while Our owner at the time was investing in some science and aging therapies and he heard about this molecule. And he heard about this molecule and they had promoted, they provided an offer to purchase the rights, the intellectual property rights, to the patented extraction process of TA-65, the molecule. So in 2002, they created TA Sciences, which is, you know, now our company, and they didn't launch the product, the supplement product, until 2007. So they didn't just take it and run with it.

Speaker 2:

We actually had to prove that it worked in supplement form and we needed to show data on that. So it's been around since 2007 on the market. We were only selling directly through practitioners then. Since then, we have published 12 clinical studies now to date and five of those are double-blind, super controlled trials. Of the 12, we have, eight of those are human trials. We started with some animal model studies in the beginning to make sure that we had the right track going with what we wanted to pursue on information.

Speaker 1:

Very good, and I was really. That was one thing that totally brought me to your company was the science. You really stand out and you know, in a lot of the longevity and anti-aging space you don't really know how much is really science and how much is a little bit snake oil out there, and so your company has done it. So so, so, so well. How long, just in general, would you say, if someone wanted to take this supplement? How long would it take for them to actually see some improvement in their telomere length after starting the product?

Speaker 2:

Sure, so in some of our study data you'll see that we started measuring at three months. This was around our mid-dose of 250 units. There's several doses you can take, but ultimately you know we talk about dosing as well in a second here. But about three months, I say being on the product is when you're going to start seeing some movement of the needle. Now this is also the situation A lot of people. There's no silver bullet out there and I have to kind of validate what I'm saying here. When you go to do something at the cellular level and you're making these changes that aren't going to necessarily produce what I'd say in the beginning exterior or invisible changes on the outside, you got to give it a little bit of time. Some people, if they're going through a very high stress point in life and they're taking this and they're still mitigating a lot of the damage that could be occurring, but they may not notice the benefits as soon. And I just want to, you know, make sure that's understood.

Speaker 1:

Right. The more threats their body's under or the more you know issues that they have, the longer it's going to take before they see or feel anything really.

Speaker 2:

Of course. I mean you probably go through this with your patients when you are about to embark them on any type of therapy, especially BHRT. Lifestyle plays a role in how well that BHRT is going to respond to what they're doing. I'm sure a lot of people can understand that the fatigue and brain fog doesn't go away as quick if you're not going to clean up things a little bit. So it's a dual effort between the practitioner and the patient.

Speaker 2:

Now, in regards to just in being on TA65, most of our data when we show the final results of what we've done is about 9 to 12 months where we show, you know, the significant improvements overall. We're talking measurable data at the cellular level on telomere length improvements, senescent cell reduction, cardiovascular marker improvements, things like that. So there's a lot of benefits that cascade down. There's also stuff that they have on brain now that they're doing a lot of data where they look at telomerase activation and the benefits of it in glial cells. Now that is not something we've pursued directly, but there is just data out there. Now there's a lot of data on telomerase and what's called TERT, t-e-r-t it's a scientific term, it's telomerase reverse transcriptase. This is sort of the mechanisms of action that allow the benefits of telomerase to affect other things besides telomeres, like, for example, shuttling TERT between the nucleus and the mitochondria. Now what this does, obviously you know we have NAD and other products that really help with that. So TA65 ends up being extremely complimentary to your other supplement therapies and your hormone therapies.

Speaker 2:

You're talking about sort of rejuvenate, cellular rejuvenation in a sense. Uh, is it? I say that so, um, but yeah, so I mean you got some time. Three months is a good number to say people. You know you got to stick to it. Cells really don't start responding to most nutritional changes until about that timeline. It's usually three, four months.

Speaker 1:

Well, that's pretty standard in the laser world too. You know we tell people after we do any kind of damage or trauma to the skin. You know it takes collagen. You know the fibroblast is going to take a few months to really rebuild that collagen and elastic tissue. So my patients are used to hearing that. So that'll be good, that's complimentary, and I you know we are so, so focused on wellness at Premier Aesthetics these days we're really excited to have the Pinoy test and all of the metabolic testing and things that we're doing. And you know telomere testing is something that we're really fascinated by. So I think having our patients come in and maybe have this test done, performed, just see what your telomere health is, and then get on this medication and then test again maybe in six months or a year and kind of see, see where you stand at that point.

Speaker 2:

Yeah, absolutely, you know, and in conjunction with other therapies, I think you would have very good results with your patients.

Speaker 1:

Well, I would. So here's another question. So say someone is really doing everything right, they're eating a healthy diet, you know they're exercising, they're getting a good amount of sleep, they're on their, you know good supplements and you know bioidentical hormone. Maybe when will that person start to like feel something from this, from this therapy? And what do you, what do people notice when they start to feel this kind of kicking in, so to speak?

Speaker 2:

Sure, so it depends, I mean it's, it is individual, no matter whether they're feeling healthy or not. So I I'll give you the best example I can give you is in of one myself.

Speaker 1:

I think, I was.

Speaker 2:

I was running along the lines of following all the rules and and and and taking care of myself, cause I started taking the product back in 2014, 20 into 2013. I started with the company at the beginning of 2013. So, after I'd been with them and I had kind of seen enough, I was like all right, I really want to take this, I really want to be on it, and I got permission to begin taking TA65. For myself. I was extremely healthy, very active. I had a special group that we'd all go do the we'd create on workouts. I was eating very clean. I had no obligations to anyone but myself, so I had a special group that we'd all do. Go do the all we create on workouts. I was eating very clean. I had no obligations to anyone but myself, so I had a very good dynamic for a, a baseline on health and and then seeing the results. The truth is for me I can be quite frank with you I probably didn't start noticing effectual changes for about seven months, six to seven months. What are some of the things that occurred? Now, for me personally, I did actually pick up on a few things. I noticed cognitive recall was improved, even though I didn't feel like I needed it. Basically, when I would go in a conversation with people, my attention span was a little bit better. I was absorbing information like names and numbers and I could recall them a little easier, for example, I can you know whereas I'd be like, oh, I met that person, I don't remember their name. Those things were coming to me a little easier. These are just nuance of changes, though, right. Another big one is you know when it came down to, because we were going through such high intensity activity, when I was working out with a certain group of individuals, back then I mean this is 10 years ago I had significant improved recovery. I noticed that I did not maintain the soreness levels that I was able to perform. So ultimately it was kind of a correlation between cardiovascular improvements and then also muscle recovery improvement. So this is just for the performance side of things. I noticed an improvement in libido, which you know you don't need it, but you don't notice it. You don't notice that those things could actually probably be optimized and I felt sort of an optimization at that level on that One of the things. Now I'm going to kind of go away from my personal deal and I'm going to talk a little bit more about a lot of the feedback we get from people on it just throughout the course of feedback into the company.

Speaker 2:

One of the things that we see a lot of, especially in older individuals, is improvement in eyesight. Now this is very specific to macular or early onset macular, age related macular degeneration dry, not after it's become wet. We had there is actually a double-blinded study that was done independent of us with a small cohort, various math cohort, where they showed within six months reversal of that. That was at a little bit higher dose where you were taking two of the capsules a day instead of one Um. But overall we hear a lot of feedback about my reading glasses I've had. I didn't need them anymore.

Speaker 2:

So it is specific. I don't think it's going to necessarily affect presbyopia um the same. However, because a lot of us are going to experience that right I think we all do at some point. But with AMD age-related macular degeneration we've seen reversal there. The other one is it is along the lines of people experience kind of the brain fog situation going away. They notice a lot of them noticed that they don't get sick. So when you have these major flu, you know like we got hit this past season. I don't know if you guys experienced it as much, but, man, we got a lot of it in Houston.

Speaker 1:

We had some really bad flu here. Yeah, the vaccine didn't seem to be very helpful this year.

Speaker 2:

Yeah, it was a strain that hit, that was very difficult and I was, you know, a lot of product and and I I have two young kids and actually an older daughter and then my wife and the whole house caught it.

Speaker 2:

The immune side is more robust on TA65, right, so I I didn't really feel the impact of that the way that I saw our family go through it. And I mean, some of these are personal, but we do get a lot of that too, where there's individuals who, because it is an immune remodeler and on that note I'll touch on this one point you know we talked about senescence, cell reduction, everything else, but there's a thing called your naive T cell reserve which we replenish. That's kind of unheard of in the supplement world. And what are naivety cells? And the easiest explanation I think I did this when I was talking to some people at your office think of them as exactly what they sound like. They're naive, they have not been assigned, they're like soldiers that are privates in the army, training for war and they're prepared to fight, but they haven't been assigned to a platoon. They don't know. They know how to, they just don't know what to identify to attack.

Speaker 1:

What the enemy?

Speaker 2:

is Right and when you have, you know, things that hit the body, this Nianticel Reserve is important to have because that is your reserve to fight against infections, things like that that are going to come attack you viruses, and we actually help replenish that reserve. So another big point in being on some of the results and benefits of TA-65.

Speaker 1:

That's fantastic and it's what's so interesting is, a lot of times, you know, as people age, you know sometimes those infections are just really harder to fight for those older people. So that's a that's another great reason for people to be on on these medications or supplements. I should say so tell me how, how young should someone start taking TA 65? Start taking TA65?

Speaker 2:

Yeah, so it's not age specific, I will say this. So typically cost comes into play too when you think about youth, and it's more the cost to value, right? So I'll start on the younger side of things. High performance athletic, young individuals you start looking at college athletes, things like that. Since this is not a performance enhancer per se, it's not going to show up on any type, it's not a drug or anything like that, so it's not going to ever cause any problems on you know, your testing and all that. But we see a lot of individuals use it for that in the youth. And, like we talked about the improved recovery aspect, you're basically just when you go through a very like hard, intense process of breaking down muscle and you're recovering, you're speeding up the cellular replication process to build back the things that you lost. And I'm not saying that you're necessarily going to grow older faster because of that, but ultimately you are burning through your you know your cellular, your telomere length, a lot faster too. So you want to do something to help support that, and I think TA65 is fantastic when it comes down to performance athletics.

Speaker 2:

The other thing is this has not been studied. I want to be clear on this, but one of my. There's one doctor here, particularly in Houston, that I work with a lot, and then there's a few others that have talked about this. In younger patients with um, adhd add, and we're talking probably the teenage years uh, they have been using low doses and have found some results in regards to their ability to refocus. So I'm hearing more about some of that. Uh, because there's things that are happening in the brain. I don't know the data on it or understand completely how that's going. I'm just giving the feedback from what I'm getting from those practitioners. Now I will say that the people that probably experience or feel the benefits the most or I noticed people that are in their 50s and older when you actually notice your body changes, everybody talks about oh, you'll feel it when you're 40. And then you really hear people saying, no, you're 50 and 60. You really feel the different things going on While we're in such a unique age and time of optimizing the body. I think we can do so many things to make our middle-aged and older years so much more viable and productive.

Speaker 2:

I think that's where a lot of the individuals notice it. I get a lot of great feedback on I love your product. I can't not be off of it. And then here's the irony they're on it and after a certain amount of time just like even if you're supplementing with really high quality vitamins and minerals you may notice you feel more energy and your brain falls on in the beginning, and then after a while you're just used to feeling great and you don't really notice that it's doing anything for you. But you notice when you stop it.

Speaker 2:

So with TA65, that's a big feedback I get is I didn't really notice I was feeling anything after being on it a while. But when I stomped it after about three or four weeks, I did notice that I was. I needed to get back on it. I wanted to because my, I could feel the optimization. So that's kind of the. The biggest thing is that you, you, you know the supplement world is a hard, a hard one to do. So we, we like to utilize testing, you know. That's why, as a practitioner, I always encourage measure their results. Really nice for them to see the numbers move on the needle with one of those numbers, yep.

Speaker 1:

So really nice for them to see the numbers move on the needle move on those numbers. Yeah, that's pretty exciting. So I've been on it gosh, probably about five or six months, and I mean I'm feeling really great. So I have not done the actual testing though. So maybe I need to do a little testing and see what's going on.

Speaker 2:

You have about up to a year to give yourself. Like you know, six months to a year is fine. I usually try to encourage people to give it about eight months or so or a little longer. But yeah, absolutely, I mean, it's fun to do so, you know, and kind of think about your life along that time span. You know, how did you feel? Was there a major stress? Were there any big events that took place? I'll give you another one. If someone's on it, they feel great but they break their arm A very unfortunate event and there's a lot of rebuilding going on to heal that arm. Your telomere length is going to degrade. That's why telomeres are malleable. They can come back, but you probably don't want to test them.

Speaker 1:

While they're not found.

Speaker 2:

Yeah, you're not going to necessarily see the most, or if they've caught COVID or the really bad flu. You know the body's really fighting hard. There's a depletion going on, and then that's why T65 is important, in the sense that your depletion won't be as bad typically, and then your rebound will be a lot better on top of it.

Speaker 1:

Perfect. So here's another question on dosage. Say you're taking one tablet a day and maybe you have one of those stressful events or you break an arm or you pull a muscle or something like that. Is there benefit to taking more during those stressful time periods?

Speaker 2:

Yes, it can be. In all of us we absorb it differently. That's why we have different doses. There are some people who it's very effective at a low dose for them. We actually have been looking at the data. We're trying to get a little bit closer, but we've kind of come around to the 80-20 hypothesis. 80% of the population is going to do really well on the standard mid-dose 250 unit. The standard mid dose 250 unit Um the years, uh more, is certainly going to still be beneficial for you.

Speaker 2:

You cannot overdose on TA 65. Uh, just um. Just another thing to note it does not contraindicate with any other supplements or drugs, so you're not going to have an issue with any overlap with anything that's going to affect it negatively. Okay, and uh, ultimately I mean you look at the dosing, so about you know you find about 10% of the population has been responding really well to the lowest dose, the 100 unit. You'll know as you go over time somebody sees their test. If the needle's still moving on those biomarkers, then that dose is working for them. If it's not, then we want to titrate that dosing upward.

Speaker 2:

And this is actually from a couple of the doctors that have been using the product in practice for more than a decade and they've been monitoring patient progress and that's how they've discovered, you know, the absorbability factor. We've actually done bioavailability testing. We know it's in the bloodstream 10 to 12 hours and we know that, yes, different people get higher, higher C, c, max, pk levels in the blood versus others in different doses. So you just kind of have to take each, each individual case. But this, you know, if you're throwing, you know what do I start? Mid dose, 250 and then 500 unit is always a fantastic place to start. You really can't go wrong.

Speaker 1:

Okay, Okay, and as far as you know GI side effects, anybody have any trouble. You know, taking this medication I haven't had any issues at all. I was just curious, if you hear it.

Speaker 2:

There's very minimal. There's not a mix of random ingredients. The only active in here is the molecule TA65. It is a natural molecule that we extract from a specific species of astragalus. The patent extraction process makes it purified enough to penetrate the cell, turn on that enzyme, telomerase. And that's where the science comes into play. A lot of people have. There are products out there that claim it. No one has been able to make the molecule bioavailable enough to actually turn on telomerase naturally. And they one has been able to make the molecule bioavailable enough to actually turn on telomerase naturally and they have not been able to prove it in human trial data or animal model data so far.

Speaker 1:

Well, this is a very cool product and it's so different in the anti-aging space. It stands out, certainly, from all the other supplements that we carry, and we are just so excited to be partnering with you guys and offering this to our clients and listeners. If you are interested in longevity and you want to do everything you can to sort of hack your biomarkers and keep yourself, you know, really really doing well long term, ta65 may be something that you want to add to your regimen. So, if you're interested at all, we carry it at Premier and we would love to chat with you about adding it to possibly your supplement regimen today. And, sebastian, before we finish up, anything else you would like to add?

Speaker 2:

I think that covers it. I really appreciate your time today and thanks for having me on. If you have any other questions, of course I'm happy to answer them, and then any links you want me to send you, or whatever you name it, I'll send it your way.

Speaker 1:

That would be great. I would love a link to you guys so that people can read a little bit more about what you have going on, and, of course, we will have the link to purchase TA-65. You can buy that at our store, shoppremieredermcom, anytime. And also come by. We would love to chat with you more about TA-65 and All Things Skin at Premier. Thanks for listening. So, guys, thank you so much for tuning in to an episode of All Things Skin. We sure appreciate you being one of our listeners. Not only do we thank you for listening, but please continue to follow us, give your reviews on any of the podcast platforms that you're listening on, and we can't wait to see you on another episode of All Things Skin.

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