
All Things Skin
Welcome to the All Things Skin podcast, your go-to resource for everything related to skin health, beauty, and wellness. Hosted by leading dermatologist, Dr. Missy Clifton, and skincare experts, our show combines cutting-edge research with practical advice to help you achieve your best skin ever.
Each episode delves into a variety of topics, from debunking common skincare myths to exploring the latest treatments and products. We bring on esteemed guests, including industry pioneers, medical professionals, and beauty influencers, to share their insights and personal experiences. Our goal is to make complex dermatological information accessible and engaging for everyone, whether you're a skincare novice or a seasoned enthusiast.
Tune in for insightful discussions, expert tips, and inspiring stories that empower you to make informed decisions about your skin health. At All Things Skin, we believe that everyone deserves to feel confident in their own skin. Join us on this journey to discover the science of beauty, one episode at a time.
All Things Skin
The Oxytocin Effect: How XOMD Is Revolutionizing Emotional Skincare
A revolution in skincare has arrived, and it's changing the way we think about beauty from the inside out. Meet XOMD – the first true mood-ceutical skincare line that's bridging the gap between emotional wellbeing and physical appearance through the science of oxytocin.
Dr. Sabrina Fabi joins us to share the fascinating journey behind creating this groundbreaking product line with her husband, a fellow aesthetic physician. Their lightbulb moment came during Dr. Fabi's pregnancy when she noticed her skin maintained its radiance despite pausing her usual treatments. The culprit? Oxytocin – the "bonding hormone" that not only helps mothers connect with their babies but also creates that coveted pregnancy glow.
The science is compelling: people with naturally higher oxytocin levels appear approximately three years younger than their peers. XOMD's proprietary jasmine-derived peptide mimics this effect by binding to oxytocin receptors in the skin's epidermis, creating remarkable improvements in radiance, hydration, and inflammation. Clinical trials revealed not just visible skin benefits, but significant emotional impacts – users reported 87% increased confidence and reduced social anxiety after just eight weeks.
What makes this approach truly revolutionary is its dual-action pathway. Unlike most skincare ingredients that work solely on the skin's surface, XOMD's formula creates a positive feedback loop between skin receptors and the brain's hypothalamus. This connection makes it particularly valuable for women experiencing hormonal transitions like menopause, when declining estrogen reduces natural oxytocin receptor binding capacity.
The elegantly designed product line – featuring Detox Cleanser, Intoxicate Serum, and Arouse Moisturizer – delivers professional-grade results while maintaining incredible gentleness. Even post-procedure patients report accelerated healing and reduced redness, sometimes eliminating the need for follow-up treatments.
Ready to experience skincare that transforms both how you look and how you feel? Discover the science of emotional beauty with XOMD – where confidence and radiance begin at the cellular level.
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Premier Dermatology is located in Bentonville, Fayetteville, & Bella Vista, Arkansas!
All right, friends, today is a very exciting day on our All Things Skin podcast. One of my really mentors and friends and just one of the kindest, most genuine humans I've ever met in the world is joining me today on the podcast to talk about her XOMD skincare, which is really kind of a really transformational idea. She is for the first time, with her adorable husband and plastic surgeon colleague, bringing us skincare that really is mood-suitical. So for the first time, we are bringing not only skin care but also emotional well-being together in a line and that is something that is very special. So, guys, welcome my dear, dear friend, dr Sabrina Fahby.
Speaker 2:Thank you so much for having me, missy. The feeling is mutual. I'm so inspired. I know you have a beautiful practice. Feeling is mutual, I'm so inspired, I know you have a beautiful practice and I find that people that have thriving practices generally the common theme behind it is that they love what they do and they're doing great things for their patients. So it's wonderful to be here with you and share that same passion.
Speaker 1:Amen, and I will tell you. I just want to give our listeners a little background into how we met. And then I want to talk a little bit about you and your adorable husband and your beautiful baby Mateo he's so precious and then how the line launched and you know just basically where you got the idea and what you're doing with the line. So first I will say dermatology is a very small world and, Sabrina, I think we met probably maybe 15 years ago at a conference and I think we were both at that point, you know, kind of just kind of getting started in our career and really trying to figure out who we were. And there was this group of really older dermatologists that were kind of the derm girls, you know, and they were ruling the roost and they were amazing humans and some of the best doctors on the planet.
Speaker 1:But I was trying to figure out how do I get to be a derm girl? I want to be a derm girl and you already were a little ahead of me and you had these contacts with these women and you were so kind to me. You brought me under your wing, you introduced me to people, you treated me as an equal from the very beginning and I just want you to know that that was a. It was a game changer for my career and I love you and I appreciate you so much for seeing me, and, and, and, and and just just being so kind and so open to sharing your knowledge and, you know, helping me to navigate that world. So thank you.
Speaker 2:Oh, it's my pleasure, of course.
Speaker 1:You're the best. Okay, so let's talk. So tell me about your practice, and tell me about your relationship with Steve, and then, and then let, and then let's talk how this all came about.
Speaker 2:Yes, so I've been, as you mentioned, in practice now for 15 years and I'm here in Southern California, in San Diego.
Speaker 2:I have been in aesthetics my entire time, so always have been doing injectables and laser procedures.
Speaker 2:And something that I came to realize very quickly, and probably where my world collided with Steve's, was that I recognized that much of the time when patients came in, it wasn't necessarily, although they would say that they wanted to get rid of a line or a wrinkle, even if you efface the line or the wrinkle, it didn't always equate to a happy patient.
Speaker 2:And so then I started wondering and questioning why I was doing what I was doing. Because I was doing what they told me to do. I was doing what you know the phase three clinical trials tell you you can do with these products. But I wasn't feeling. I wasn't feeling fulfilled because my patients weren't happy. And so I started and I've published a great deal on like the psychology behind why people do what they do, how to not slip into looking peculiar with perception drift, um, and then also how to like, not impose our bias onto our patients are of beauty standards, like with our aesthetic bias as practitioners, and I started realizing that there's usually patients don't know necessarily what they're coming in for, but they know that they want to feel better from the things that we're doing.
Speaker 1:And so.
Speaker 2:I realized the power of what we do and we're in this unique, I think, very privileged position with our patients that I try to honor and respect, and that is that we can really help them feel better about themselves. And you know, it starts to make you wonder is feeling better about yourself, then? What makes you look better? Right, looking better definitely can make you feel better, but that doesn't always equate to be true, because we see some of the most beautifully, mathematically perfect women which is what Steve always publishes on and they're not necessarily the most attractive person in the room, they're not necessarily the happiest person in the room.
Speaker 2:So there's an opportunity, really in the consultation and in the relationship that we forge with these patients of ours, to really try to understand what's the driving behavior behind why they want to do what they do, and then meet them with the right procedure, you know, and that's a blend of, obviously, psychology and then having an aesthetic eye and then obviously having like, the skill set with your hands to be able to like execute that plan. So there's definitely an intersection between mind and mood, right With what we do when it comes to beauty. So and I think that once I started writing about it. I write generally to almost learn and it's almost like my therapy right In learning more about it. I write generally to almost learn and it's almost like my therapy right In learning more about it.
Speaker 1:Journaling is a big thing, yeah, right, yeah. And I think you know the thing that I love about you as a human is I think you see people Not every doctor actually sees the patient in their chair and I think you have the unique capability, like I. I feel, like my patients tell me I have it that when they come in I'm not just looking at you know what they're telling me. I'm saying, okay, they're like I hate these lines. I'm like, okay, but what else is happening? Where are you in your hormonal journey? Where are you in your relationship journey? What is happening at home? Because I can fix your line, I can give you a little lift, I can tighten up your skin, but at the end of the day, I can't fix what's going on at home and I can't fix you know what else is happening? I can't fix. You know what. What else is happening. So I think there is a real push in all of all of medicine to go beyond the aesthetic, even to go beyond the, the medical lab results. Yes, and look at what is psychologically happening in your world and how do we help you manage that? Because you can look like you said. You can look like you said, you can look mathematically like the most perfect person on the planet, and I have women come into me every day. I'm like, babe, you are the most beautiful woman I've ever seen. You have no body fat. You are perfect. But they're miserable. They don't feel the value that they need to feel for themselves, and so I think what you're doing with this line is really, really exciting and it's something so extraordinarily different. So you and you and Steve are married and you have.
Speaker 1:Honestly, I love watching you guys on Instagram. I love watching your story. I've known you long before you guys on Instagram. I love watching your story. I've known you long before you guys were together and to see your joy and your happiness and this beautiful, beautiful young man, mr Mateo, that you guys have created, it is such a joy to see you be a mama. Thank you, because I knew you before you were a mama and you are a. You're everything I knew you would be, because you're a badass and everything that you do, but you you're killing it as a mom and as a wife, and I love seeing you're happy. It really makes me so happy to see you happy.
Speaker 2:Thank you, the feeling is mutual, my friend.
Speaker 1:So tell me about how you and Steve got together, and then let's talk a little bit about you. Know how the concept for the line came about.
Speaker 2:Yes, so Steve and I met shortly after I got divorced. Now it's going to be 11 years ago and I met him six weeks later. So for all those people going through that, you never know when you're going to meet them even when you're not ready for it.
Speaker 1:Amen baby.
Speaker 2:We've lived across the country from one another. He still resides in Chicago, and so that always posed a little bit of a difficult challenge until in about six years into the relationship, when we were on and off, we decided that, okay, well, maybe if we decide that we're not going to have a baby, then, you know, being like having this distance between us wouldn't impact things as much, and so decided to move forward with our relationship. We got engaged in 2021 after we had already decided that we weren't going to have a child and we were going to continue working across the country from one another. We share very similar viewpoints on the impact that we have in what we're doing and also what drives us to do what we're doing, and that's really to make people happy not necessarily just to efface a line or a wrinkle.
Speaker 2:And so in 2022, I spontaneously got pregnant. Two, I spontaneously got pregnant, so that is possible, too, when you're 42 years old, even if you have had fertility issues. And and it was a most beautiful time in my life- I, I loved being pregnant.
Speaker 1:You were well, you're already gorgeous, but you had this incredible glow that I've never seen. I mean, you were just a stunner and you were up on stage teaching, super pregnant, and I was like go moms, and you know what wives and moms can do and still be great wives and moms. We can still make a huge impact and have the career. We can have it all. Yes, if we do it well and if we, if we prioritize things and you are such an example of that and you've really you've done it so well, sweetheart. Thank you, you really have Thank you, yeah.
Speaker 2:So during this time now I had gone now for 13 years I'd been doing aesthetic procedures and all of a sudden, in the middle of my 40s, I'm not able to do them because I'm pregnant and then breastfeeding. But I felt great and so, just like any part of my career where I like to understand why whether it's my motivations with patients or how to make them look better without making them look unnatural you know we were researching why, like I'm, like gosh, it's like you know, is it because I have a boy and I could have higher testosterone levels? But like no, I don't see increased hair anywhere and my voice is definitely not deepening. And now, when we're pregnant, we definitely have higher levels of estrogen and they go exponentially up throughout the trajectory of that pregnancy, which can definitely have an impact on mood Not always good, though Not always for the mood, not always for good, not always good, though Not always for the good, not always for the good. You can also be hypervascular with estrogen, which you know we lose when we're going into menopause, and that in that patient that's wonderful.
Speaker 2:But it's not like I was in menopause because I was pregnant, so I couldn't attribute it all to estrogen in menopause because I was pregnant, so I couldn't attribute it all to estrogen, and so you know what was contributing to like that dewiness, that radiance and not making me look as haggard as I should look, having been off the treatments for like nine months. And so I looked at a paper in 2021 that was published actually in the JDD. In 2021 that was published actually in the JDD. And it was funny because, like nothing's by coincidence, I had already flagged this paper about two years ago, because it was interesting to me that people that had higher oxytocin levels just organically looked about three years younger than their same age counterparts that had even more. Like you could have high oxytocin levels by serum and have even more history of photo damage, but still have a younger age or look younger than somebody who had lower oxytocin levels, and so that was interesting to me. I'm like so there's something there, and why haven't we explored that?
Speaker 1:So oxytocin is something that no one's looked at in really in skincare, or in a lot of ways no one's really looked at it. Can you tell our listeners a little bit about oxytocin?
Speaker 2:Yeah, so oxytocin is a hormone that is biologically intended to make you bond with your infant. It also goes up when you're pregnant, not necessarily linearly, but it's higher at the end of pregnancy than in the beginning, as you get ready to breastfeed and bond with your baby, and so that's its biologic purpose. It's also, I think, interesting because it's an anti-inflammatory hormone, and so that's like its biologic purpose. It's also, I think, interesting because it's an anti-inflammatory hormone, and so we know that pregnancy is likened to one of the most three stressful physiologic conditions that anybody can ever go through, and it's likened to trauma or having undergone a massive surgery, because the physiologic shift that you go through when you're pregnant is extremely intense for the body, and so you are in this kind of hyper inflammatory state Physically emotionally all of it, everything right so oxytocin.
Speaker 2:Almost it's smart, like mother nature doesn't make a mistake, like it's intended to almost also counteract that inflammatory state because it prevents reactive oxygen species from forming free radicals that ultimately break down more collagen, elastin, but also overall for your body, put you in a worse state and so it continues to go up as you continue to get bigger in pregnancy and then when you meet your infant. It's intended to make you bond with that infant. It promotes like a feeling of fidelity, closeness also true with your romantic partners. The effects that it has on men are slightly different than they have on women, but for women it does make you feel more close to your partner. For men it promotes a feeling of not wanting to stray from your partner.
Speaker 1:Well, we might need to put it in the water, Sabrina.
Speaker 2:So it's very interesting for Steve, who is fascinated with just evolutionary biology. It's a perfect, you know, neuropeptide for him to study. But for me it was interesting because as a dermatologist I started wondering okay, so it's secreted by your hypothalamus in your brain, but it's also secreted at the level of your skin. So it's one of these few peptides that can have a positive feedback loop, in that when you hug and touch, it goes up when you touch these mechanical receptors on your skin. That's why it's released when you hug or you hold someone for more than 10 seconds. Everyone has kind of maybe heard about that. You have to hold and hug for more than 10 seconds.
Speaker 1:Or a baby breastfeed.
Speaker 2:Huh.
Speaker 1:Or a baby breastfeed Right, which is hard.
Speaker 2:Yes, yes, like that skin-on-skin that we talk about, right, which also that goes to another topic which is like also the microbiome that is being interchanged with the baby, but nevertheless so it's intended for you. It makes you feel good, right, that holding, that kissing, that hugging. There's a reason why that makes us feel good, why we search for that. So when that is released from holding and touching, it's because when you touch these specific piezoreceptors that are mechanical receptors that are at the level of your skin, are bounded to and then they release oxytocin. So you can have a positive signaling at the level of the skin, which then triggers a positive signaling release in your hypothalamus, in your brain. So usually when you have something going up at the skin, you have a negative feedback loop later on or more distally, but here it can be positively happening at your skin and then it's positively happening in your brain, making you feel more relaxed. So you feel more relaxed after the long hug, you feel more relaxed after the breastfeeding. Some women even report falling asleep after breastfeeding and it's not necessarily because you're sleep deprived, but it's because it's a hormone that makes you feel more relaxed and less anxious.
Speaker 2:Amazing, and so it was really interesting to me that we have receptors already available to us at the level of the epidermis, the very top layer of the skin, but no one had thought about potentially looking at that as a receptor, especially if there's a possibility that once you bind to it, you can have downward signaling into the second layer of the skin, the dermis, and there are receptors for oxytocin on your fibroblasts in addition to your keratinocytes, which are the top skin cells. So we started looking for PhDs that are doing work in neuropeptides to try to find somebody that could help us formulate or create a neuropeptide that has been found, in vitro at least, to bind to the receptor, and we did. And so, as you know, the in vitro work, things that are done in labs on tissue, don't always translate to clinical effects, because many of these products are sometimes not stable in the vehicles they're in or sometimes the molecule itself is too big to actually be absorbed and have the effect that it should have.
Speaker 2:So we decided to test it clinically and we didn't know. I mean we just we do things, you know, because we're I mean I do all kinds of studies all the time. Some things pan out, sometimes things don't, but sometimes you get some breakthroughs. And we were curious. If the receptors are already at the top layer of the skin, it doesn't necessarily need to penetrate, so it doesn't matter what size it is.
Speaker 1:So is. It is the receptor in the receptor in the papillary dermis, epidermis. It's in the keratinocytes, it's in the keratinocytes of the epidermis. Okay, amazing. Yes, so it really needs to barely get in.
Speaker 2:Yes.
Speaker 1:You don't have to get in the dermis, like a lot of these things where we're trying to rebuild collagen and elastin. It just has to get through the stratum corneum and into the epidermis. Amazing, okay.
Speaker 2:Love this, right and so. But could you get enough? Then the question always becomes can you have enough bind to then create a cascading effect to get the benefit in the dermis? Because it's in the dermis where you have your blood vessels that cause redness. It's in the dermis where you have your collagen and elastin and your fibroblasts. It's in the dermis where you're trying to. The reason we get dewy and radiant in pregnancy is because it's in the dermis where oxytocin draws in water to the dermis. So that's why you kind of like get plumped up during pregnancy. So it's not just because you know we gain weight and so we did a trial.
Speaker 1:It's responsible for that glow. It's responsible for the glow that everybody, the glow of pregnancy that everybody talks about, and I've never, ever heard a scientific reason for it. This is blowing my mind.
Speaker 2:a scientific reason for it. This is this is blowing my mind a little bit, yes, but if you read about it it's. There's actually literature in the plastic surgery literature way before this where they hypothesized that oxytocin actually binds to the insulin growth factor one receptor. So you can have, it promotes wound healing because of its anti-inflammatory nature and we know that it makes sense postpartum right, pardon me, wow, that makes sense.
Speaker 1:Postpartum, yes, because that's when your whole body's trying to really heal.
Speaker 2:That makes a lot of sense, and you're responsible for making a bunch of milk in this super inflammatory state and so it's. You know it's a lot on the body, it's a big toll. You know you're hormonally hijacked is what I tell my patients. Right, it doesn't just happen in perimenopause or menopause. Women have to go through these cycles and gosh if you've had two kids or three kids every single time and it takes about some studies report 12 to 18 months after you deliver your child for you to achieve homeostasis again.
Speaker 1:And I had two at once, sabrina.
Speaker 2:So that explains why I was a little bit psychotic, maybe I mean you're on a high with all this hormone and then it's like overnight at drop. That's a lot to ask of our body Right. And now that there's more attention about the hormonal implications on the skin, which you know, we didn't realize that all of this data about HRT was going to be refuted in this year Like it just all. But there's a lot more information coming to light about the benefit of you know, it's not just collagen and elastin and it's there's hormones at play that also affect the health of our skin right Now we know, like interesting work done by Zoe Drelos, how about like topical estriol and estradiol? You have no systemic effects from it, but you can have an improvement in your lines and wrinkles and an improvement in doing this.
Speaker 2:But of course, not all women need that topical estrogen when they're perimenopausal or have just gone through a baby. So what can you do for those women to get that glow and that radiance? So we did the study and we did a placebo controlled. We took 20 women and only put them on the vehicle of the serum and the moisturizer, without the active. The active has been derived from jasmine and it's a peptide, just like many of the peptides, not synthetically made, but it's actually derived from jasmine, and it's a peptide, just like many of the peptides not synthetically made, but it's actually derived from jasmine. And that is what in vitro was found to bind to this oxytocin-like receptor. And so we put it in this vehicle and we did stability testing on it first, which is necessary in the United States.
Speaker 2:For those who are listening, it's not just like you can whip something off in your kitchen. You actually have to do these things. And so we then used it on our patients, and so we looked at metrics of the skin that we knew could potentially improve, like radiance dewiness. Theoretically, you should see an improvement in dryness if you have increased dermal water capacity, a decrease in redness if we believe in the data from the plastic surgery literature that it's anti-inflammatory. And then we also looked at lines and wrinkles almost as like kind of our metric. We shouldn't have seen an improvement in lines and wrinkles because we were only using it for four to eight weeks. So you know that if you're going to bind to the fibroblast, that should take like 12 weeks to really have an impact, at least three to four months yeah.
Speaker 2:Right. So it's like a sanity check, Like okay, is this just you know? Like, really does it work? And we found, in as early as four weeks, every metric improved except lines and wrinkles. The most notable ones were redness and dryness and radiance, which makes sense because that's what you see in pregnancy, right? Then we took those images and we populated them through SurveyMonkey and we randomized them. We didn't put before and after, but we just put the image itself. So people didn't know if they were looking at someone on product. No, product didn't know. I want to say it was like over 500 people that rated random images, rated random images and the people that were on XOMD, after just four weeks, on average look three years younger than the people that were not, which it's not random that it was three years, because that's exactly what the trial in 2021 showed, which was people with intrinsically higher levels of oxytocin look three years younger than other people. So it's like we can mimic those types of results if you're on this topically.
Speaker 2:So we were very excited and then Steve, you know, wanted to see if we could do more, Like I was happy with just the skin metrics. But he was like well, is it having a positive feedback loop in the hypothalamus, Like we should expect it to see. And so we did like different mood questionnaires and it wasn't significant on any of them except social anxiety, which is what we know. It's an anxiolytic. It doesn't help with depression or anything like that, but it helps with your anxiety so it makes you more relaxed and comfortable in your own skin and that was statistically significant. And then when we looked at confidence, people by eight weeks on it, so two months reported 87% increase in being more confident. So it's not like you can say, oh well, I'm just using a topical product and now I'm doing something regularly, so I must just my skin looks better and I feel better. The people that were on the placebo did not show a significant improvement in confidence.
Speaker 1:That's definitely the active.
Speaker 2:Right. So there was something there. And then, a step further, we asked people on different sexual satisfaction questionnaires, because oxytocin is intended to make you bond. Now, for women it's supposed to. If you have higher oxytocin levels, it makes you trust others a little bit more. It makes more masculine faces appear more trustworthy, and so we again asked women, and we found that women perceived men more attractive. So it's actually it's a great gift to give a woman technically, because it makes you come off more attractive if you're the man. And so in the bedroom, women reported like faster onset of like orgasm and other metrics when we looked at sexual satisfaction, and I think it has to do with feeling more bonded to their partner.
Speaker 2:And partners even noticed the difference in. The partners were like triple blinded, so it was almost too good to be true. But how would the partners ever know? So there was something definitely there, and we're hoping now to repeat the trial using potentially having women that are going through menopause or already in menopause. We know that when you're going through menopause, a drop in estrogen decreases your oxytocin receptor binding capacity.
Speaker 1:Wow, I did not know that.
Speaker 2:So even if you're in love, or you're you know you're holding that baby. Your ability to feel that feeling of oxytocin diminishes when estrogen diminishes.
Speaker 1:Wow. So another reason why HRT you know when appropriate is so powerful because it helps you also bond better, right? Yes, it helps you to feel confident again, to feel sexy again to you know all of the things that are supposed to happen when you're feeling amorous actually happen, which is really lovely. And then you also have the desire, because I think that is the thing with so many women, especially in perimenopause. You know you see relationships fall apart all the time and you know it's not only physiologic, it's also emotional and it's also that that bonding that you're talking about, that kind of starts to fall apart. So this is incredible to hear.
Speaker 2:Yes, wow, I know we were, we were, we were pleasantly surprised. I mean we don't really need to put anything out there. I mean we come up with ideas, naturally and, you know, present them as keynotes and in lectures all the time, but to really we wanted to create something that can have an impact, a positive impact, on just the overall wellbeing of women, especially since the average woman that I see is about 47. The average woman Steven sees is about 55 for facelifts, blephs, you know. And so we recognize that those women are going through hormonal shifts. Those women are going through hormonal shifts and maybe that sometimes has an impact on their perception of the benefit from treatment, happiness from treatment and how they feel about themselves. Right, absolutely, and so if we can support that hormonal health of their skin and mind, I think that we can also just see better impacts from the treatments that we're doing.
Speaker 1:This is kind of blowing my mind a little bit. Thank you, I knew this was going. I knew talking to you would be amazing, so I, you sent me your products and I have used them and they're lovely. They're so cosmetically elegant, they feel good. They're not, they don't have like an overpowering fragrance. I mean they're not they. They don't have like an overpowering fragrance. I mean they're just lovely. They make my skin feel very hydrated, very plump, and I I love them. And maybe it's the oxytocin. I didn't even know that I was loving them. But you know, I'm in a. I'm in a a post-divorce situation as well and I will tell you I I just feel like anything that you can do at this point this post-menopause, post-divorce, post-whatever we are in in this stage of our life to just make us feel confident and happy and safe in our skin. It's a big deal for women in their 40s, 50s and beyond.
Speaker 2:Yes.
Speaker 1:And I think you're really on to something and I'm so impressed and so proud of you and I really want to hear about the different products. Talk to me about each one. And then we've got to figure out how to get them into Premier, because I need my patients to be able to purchase these products easily and come by and get them. So talk to me about the different SKUs in the products line.
Speaker 2:Yes, so we start with the cleanser.
Speaker 1:When I created the cleanser because I do a lot of fully ablative CO2 laser resurfacing and for those I don't know if you do them, missy, but I do a lot of Erbium, so, yeah, my patients know about the deep halo resurfacing and you know it's it's it's a take your face off big time procedure. Exactly, it's a big deal and you need.
Speaker 2:sometimes. These gentle cleansers that we recommend over the counter are gentle, but they also don't remove some of that serosanguinous crust that can be a great something that you bacteria loves to snack on and then, before you know it, you have an infection day four, day five. So I wanted something gentle enough that I can put it on a post-op laser resurfacing and I'm talking fully ablative CO2 layered with fully ablative erbium, like day three, and it doesn't burn my patient's face. So that was like the vision for the cleanser right.
Speaker 1:That's why you call it a detox. Get rid of all the badness that we've done to you. Get rid of it. Get rid of it.
Speaker 2:And also, just we know that not washing your face, just the daily grime that builds up on your face, especially San Diego is considered like the sixth most polluted city in the country. So if you're a runner and you're out there, I think you're a runner, aren't you?
Speaker 1:Oh baby, I used to run and now I just don't run anymore. Now I'm a Pilates girl and a weightlifting girl. But back in back, when we first met, yeah, I was running, I was like doing 5Ks, 10Ks, I did a Tough Mudder. I think the first year we met each other.
Speaker 2:Yeah, you were running.
Speaker 1:Now, if you see me running, I've probably been snatched up by body snatchers and they've taken my brain out, because the running just doesn't work for my body anymore. I'm with you, it doesn't work for my body anymore. I'm with you Doesn't work. So, yeah, but I get it. But I, we, we are. I'm outside all the time. I love to bike, I love to hike, I love to walk outside.
Speaker 2:So, um, and there's a lot of pollution in the universe that damages your skin Can definitely age you and there's some great studies on how it could increase your pigment by about 20% and it can increase, you know, just overall lines and wrinkles over time. So getting the grime off your face is important and so that's why it's called detox. Then comes the. So it's gentle enough to not irritate your skin, cause I, you, were dermatologists. You know everyone that comes in has sensitive skin or self-report sensitive skin. We're doing layer lasers for redness, so it has to be with that, that person, in mind. Then intoxicate, intoxicate and arouse. Or intoxicates the serum, arouse and it's a kind of a play on the effect that they have. That's the serum and that's the moisturizer.
Speaker 1:And there's I love the packaging. I designed it. I love it so different.
Speaker 2:They're X's and O's, so, and I wanted it to look nice like on a bathroom counter or even in a retail space, because we're in aesthetics, these products are so expensive and they're in like these cheap plastic bottles, you know. It just always is like. I'm like is there no consideration that we're, you know, in aesthetics, right? So I'm sensitive to that. So I wanted what was in it to match what was outside.
Speaker 1:So you did a great job. They're beautiful, thank you.
Speaker 2:And so here these two have the OX factor, which is the proprietary blend of the phytopeptides, and then there's also carob, and so that's what's having the effect on the mechanoreceptors, on these piezoreceptors. But in the serum we have also an extract from like honey tree that comes from Korea and China. That has been found to decrease pigmentation. So that's unique in the serum. That's not found in the moisturizer, which acts a little bit longer than most HAs, because the problem with hyaluronic acid, depending on the formulation you get. There's various formulations. Some of the over-counter stuff is just like free HA. We know free HA vaporizes within 15 minutes of being on the skin. Some of the more cross-linked HAs just don't get absorbed. So it was coming up with something that can add to drawing in.
Speaker 1:Penetrate and then pull in the water. Yes, yeah.
Speaker 2:And then Arouse is the moisturizer and it serves as a nice humectant to kind of seal that top layer of skin, using glycerin as its base.
Speaker 1:That's why it feels so good. Pardon me, it feels so good Good, yes, it does. It's very soothing.
Speaker 2:And that was the goal, because sometimes some of the other ingredients that are a little too fatty just sit on the skin as they can't get absorbed Right, and I wanted to be able to put something on, especially after some of the aggressive lasers that we do for my patients, so that they could heal faster. And so that it was like thinking of the vehicle. It was like, okay, I love the ingredient of OX, but I need it to be in a vehicle that my patients can tolerate, so I'm not adding another problem and then they're coming in for a different problem.
Speaker 1:Thank you for that. So I had the ultra clear device done on Monday, with some laser coring under my chin and my forehead. So I used your cleanser oh great, yes, because I didn't know how safe it would be to use the serum and the moisturizer. But I knew that your cleanser because I had used your cleanser right after microneedling and I'm like this just feels so good and there's no stinging, there's no burning. So I was already like sold on the cleanser 1000%. But post-treatment, how soon can we use these products?
Speaker 2:So after, like if I do a non-ablative, so if I do, I usually do a combination of IPL Pulse Dye Laser with a Clear and Brilliant or IPL Pulse Dye Laser with, like a Fraxel Dual or Fraxel Restore. I put it on immediately on the table to draw in water to the skin. So I usually put the Intoxicate Serum first to draw in water. Then I even use on top of that I like to use the SkinCeuticals Phytocorrective Mask to cool the skin.
Speaker 2:And then I'll put on, before they leave, the Arouse Moisturizer, so that they can go on about their day, especially after the restore.
Speaker 2:They tend to report that their face feels on fire, and so that's been great. I also do it immediately after photodynamic therapy, because that way it's not so so greasy either that for my acne patients it's causing another issue. So for those folks, those procedures that's what I do or even a microneedling RF we use, like the Potenza For fully ablative resurfacing. I won't use this until they re-epithelialize at day seven or day 10. But we historically, as a practice, have always, because of how aggressive we are with our CO2, they still have post-op erythema week four.
Speaker 2:So we've always offered like a post, a complimentary pulse dye laser. But now that I'm using this day seven, day 10, by day 28, day 30, their redness is pretty much gone. So I don't need to offer them the PDL like I used to. So it's great because it's decreasing the redness and that's always the hardest thing for me.
Speaker 2:It is the persistent redness that drives people crazy, crazy, drives people crazy, and even with melasma right, Like there's the vascular component of melasma that we can't get. There's such great things for melanin, but that it's that erythema right, Whether it's from rosacea, PIE or in melasma or from the procedures that I do. So it's been great for that.
Speaker 1:Well, I want your protocols. So I want to visit with you offline because I want your protocols and I want you to tell our listeners, first off, how to how to how to order your product right now, yes. And then I want us to to chat about how we bring the product line into premier, because I am sold and I absolutely I want my patients here in Arkansas to you know glean all of the wisdom and all of the all of the science behind what you've put into these products. I'm really impressed.
Speaker 2:Thank you. Thank you so much. Let's see, yes, so for those who are, right now.
Speaker 1:Is there a website where they could go? Okay.
Speaker 2:XOMDSkincom.
Speaker 1:Okay, all right. Well, you guys have done something really special here, and I think it is so incredibly innovative. And I am not surprised, because I know you have this huge brain and so does the really amazing husband that you have, and I'm so happy for you and I just wish you all the joy that you deserve, my dear, because you're an amazing person, you're an amazing doctor, you're an amazing mom, an amazing wife and now even a more amazing scientist. So I'm so excited and I can't wait, and I would love it if you would come to Arkansas sometime. Oh, I would love that I haven't.
Speaker 1:I would love to come out to visit you as well. So let's make it happen and let's talk about how to get XOMD into premier dermatology.
Speaker 2:I would love that.
Speaker 1:All right. So, gang, thank you so much for tuning in to another episode of All Things Skin. Thank you for listening to my beautiful colleague, sabrina Fahby, and I can't wait for you to learn more about XOMD. So tune in next time for another round of All Things Skin. So, guys, thank you so much for tuning in to an episode of All Things Skin. We sure appreciate you being one of our listeners. Not only do we thank you for listening, but please continue to follow us, give your reviews on any of the podcast platforms that you're listening on, and we can't wait to see you on another episode of All Things Skin.
People on this episode
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Dr. Missy Clifton
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Becky Carroll, RN, CANS
Co-hostBrian Clemson
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Brisa Castaneda
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Brittney Matthews
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Chris Murray
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Connor Roberts
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Danyelle Musselman
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Dr Samuel Lynch
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Dr. Blake Williams
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Dr. Caroline Cunningham
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Dr. Kattie Allen
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Dr. Lance Manning
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Dr. Laura Battle
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Jenny Marrs
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Jocelyn Maddox
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John Garruto
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Jon Williams
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Jordan Patterson, RN
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Josh Throne
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Kara Richardson, P.A.
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Kimberly Mann
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Lacey Goldwire
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Lexi Fields
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Lindsey Jeffs-Elkins
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Linzy Elliott, DNP, FNP-C
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Lynn Carson
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Marie Carell
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Phil Rouse
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Reggie Gatewood
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Savvy King
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Sebastian Conti
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Shawn Towne
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Stephanie Venn-Watson
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Tatiana Kononov
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