Peptide Power: Revolutionizing Wellness and Regeneration

Unlocking your body's natural healing potential might be simpler than you think. Peptides—those tiny chains of amino acids that serve as your body's natural messengers—are revolutionizing how we approach wellness, weight management, healing, and even cognitive health.

Unlike pharmaceutical medications that flood your system with foreign compounds, peptides work through precision signaling, telling your body exactly what to do without disrupting other functions. This targeted approach explains why they deliver remarkable benefits with minimal side effects. While many people now recognize peptides through weight loss treatments like Ozempic and Mounjaro (GLP-1 agonists), their potential extends far beyond shedding pounds.

The real magic happens when peptides are strategically combined. For weight management, lower doses of GLP-1s paired with muscle-preserving and visceral fat-targeting peptides deliver healthier, more sustainable results than pharmaceutical megadoses. For healing, compounds like BPC-157 and TB500 work in concert to reduce inflammation while accelerating tissue repair—whether you're recovering from surgery, managing arthritis, or bouncing back from intense workouts. Growth hormone peptides restore what naturally diminishes with age, supporting everything from sleep quality to tissue regeneration. Perhaps most exciting are the cognitive peptides that cross the blood-brain barrier to potentially prevent neurodegenerative conditions and enhance mental performance.

What makes peptide therapy truly revolutionary is its personalized approach. Through specialized assessments that analyze your specific health concerns, lifestyle, and goals, practitioners can now create customized peptide protocols tailored precisely to your needs. Ready to discover what peptides could do for your health journey? Visit NudaLabs.com to take their quick assessment and find the peptide combinations that might transform your wellness from the inside out.

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Chapters

• 0:00 Introduction to Wellness and Peptides
• 6:10 What Are Peptides and How They Work
• 10:59 Metabolic and Weight Loss Management Peptides
• 20:09 Healing and Regeneration Peptides
• 28:13 Growth Hormone Peptides

Transcript

Speaker 1: 0:00

Hello, friends, and welcome to another episode of All Things Skin, and today we're talking about wellness. It is kind of my new obsession, as many of you know, and today we are talking about a collaboration that I have with a dear friend named Dr Nick Ogle and his beautiful wife Chani, who have co-created a company called NUDA Peptide Therapeutics with me and we are partnering together to bring the safest, most advanced peptide technology and treatment methodology to premier dermatology, aesthetics and wellness. So I cannot wait to talk to you today about peptides, because I'm personally taking peptides and they've kind of changed my universe. We will be having a future podcast where we bring my partners in to talk about how peptides have changed their universe and why we have partnered together.

Speaker 1: 1:01

But today I want to just give you a little background on what peptides are, what the different really you know big categories of peptides are and which ones within those categories do specifically what they do in your body. So let's give it a start. So, first of all, what is a peptide? So I'm going to play a little video here so that you can listen to the discussion, and then I'm going to talk to you a little bit more about what a peptide is.

Speaker 2: 1:36

Peptides the building blocks of a revolution in health optimization. Peptides are short chains of amino acids, the natural messengers of the body, regulating essential functions. Unlike medications that alter biochemistry or supplements that provide nutrients, peptides work by signaling the body to take action. Found naturally in the body, peptides send signals to trigger healing, improve cognitive function and support gut health. Improve cognitive function and support gut health. Some well-known peptides include GLP-1, now known as Ozempic Manjaro, and others used for weight loss and blood sugar control. Bpc-157 is known for gut health, tissue healing and many other benefits. Peptides aren't new. Insulin, the first peptide therapy, was discovered over a century ago. Today, scientific advancements are unlocking their full potential, paving the way for more targeted and effective applications. From anti-aging and weight loss to cognitive function and recovery. Peptides offer precision-based therapy with fewer side effects than many pharmaceuticals. Backed by science, peptides are shaping the future of personalized medicine. Visit our website to learn more.

Speaker 1: 2:57

So, as the video said, peptides are these tiny little molecules that are the precursors to protein. They're just little tiny chains of amino acids that, when they are injected into your body, they go to specific places to turn on and turn off switches. In some cases they turn off your appetite, like as the GLP-1. So a lot of people have been taking GLP-1s like semaglutide, terzepatide, manjaro, all of these others that are out there now to really lose weight. But what we don't realize is that there are also a lot of peptides out there that can help you maintain muscle mass. They can turn on growth hormone secretion. When growth hormone goes away, they can turn off inflammation. They can do lots of things in your body very specifically without causing lots of other side effects, which is what is really really amazing. Most of the pharmaceutical medications that we take, you know, they go into our stomach, they get absorbed into our whole body and they have all kinds of effects on cells and they have all kinds of other interactions with other medications. But peptides, because they are already natural endogenous things that your body is used to that are signaling proteins and signaling peptides they actually target very key things that are happening in your system without causing side effects, without causing drug interactions and without causing a lot of the other potential negatives that a lot of the pharmaceutical medications can. So what we have found is that a lot of times, using peptides in conjunction with each other, like the GLP-1s, a lot of our patients use them at very high dose that the pharmaceutical industry was recommending, and patients lost weight very, very quickly. They also lost muscle mass. They also lost bone mass because that rapid weight loss was not really healthy. So now what we're learning is that those GLP-1 peptides can now be used in a much smaller dose. Maybe you can use them also with other peptides that help to you to maintain your muscle mass and help you to maybe mobilize the fat that's in your visceral area, which is the fat around your organs, which is the most important fat for elimination if you want to have longevity the fat in our subcutaneous tissue. Of course, we want to eliminate a lot of that too if we feel like we're overweight and we're not at our goal weight. But the really dangerous fat is the visceral fat, the fat around your organs, and there are actually peptides that can actually target that fat and help your body get rid of that. So I'm going to talk to you about several different categories of peptides today, and the first one we're going to start with is the metabolic and weight loss management peptides. These peptides help support healthy metabolism, fat utilization and appetite regulation, and they work through these natural processes that your body has always used, rather than forcing these unsustainable changes that you might get with, say, intermittent fasting or a full vegan diet or full you know maybe you want to go paleo. There's lots of different diets out there, but they're not really sustainable in a lot of ways, and so peptides can actually suppress your desire to eat, but then they can also help your body to really store muscle and to get rid of the dangerous fat. So let's talk about some of these peptides that are out on the market right now.

Speaker 1: 6:34

There's trisepatide, which is Mojaro. It is a combination of a GIP and a GLP-1 receptor agonist, so it supports blood sugar regulation, appetite control and metabolic health. There's also semiglutide, which is juiced, a GLP-1 receptor agonist, and that's Ozempic, regovi and now Rebelsis, and those are the ones that actually have a pharmaceutical company that has created these drugs. There are also compounded versions of these medications that are very safe and that you can actually use in much lower doses so that you don't get the slowing of the GI tract that you can often get with higher doses of these medications. Often with the lower doses you don't get the nausea but you also get the long-term metabolic effects at these lower doses that your body intended to have these peptides used for. These peptides are actually made in your GI tract in tiny, tiny doses. So I think the mistake that has been made in the pharmaceutical industry is we have given people massive doses of these medications that then cause a lot of the slowing of the gastric emptying, so that people you know have a lot of reflux, maybe not great absorption, and really the beautiful thing about taking them at lower doses is that you don't have those side effects but you get all of the benefits.

Speaker 1: 8:02

And when you combine them with other peptides like AOD-9604, which was originally developed for fat loss, it actually helps mobilize the fat in your body without affecting your blood sugar, which is kind of magical. And then there's also a metabolic and weight loss management peptide called MOTC. That is a mitochondrial derived peptide. As you remember mitochondria probably you remember this from like eighth grade science the mitochondria is the powerhouse of your cell. So what this peptide does is it helps to support mitochondria, and your mitochondria is responsible for all of the energy production in every cell of your body and every organ in your body. So if we can support that metabolic health in every part of your body while we're also suppressing your desire to eat and then also mobilizing the dangerous fat, then we can really get amazing results without the negative side effects that we get from some of these peptides alone. So we can get improved glucose metabolism, enhanced fat utilization, appetite regulation, metabolic support and also overall body composition support. So really exciting what we can do with the combination of some of these peptides.

Speaker 1: 9:26

There are also peptides that are pretty incredible for healing and regeneration, and these peptides support tissue repair, reduce inflammation, accelerate wound healing and recovery. Maybe you had a really hard workout, maybe you actually have had a surgery that you really need to recover from, and these peptides work through multiple pathways to really improve healing and help your body to just recreate that homeostasis, that healthy living environment, so that your body can repair and really recover from anything, any kind of stress out there that you have placed on your body. So BPC-157 is also called Body Protection Compound 157, and it has shown remarkable healing properties, not only for the skin, the nerve tissue and the gut, but any inflammatory process in the body. It can help you recover tremendously. Tb500 is derived from the naturally occurring thymus. It is a gland that helps regulate your hormones, and it plays a vital role in cellular migration and tissue healing. So there are a group of peptides that are really responsible for helping your body heal and regenerate, and that can you know.

Speaker 1: 10:48

Anything can cause the injury. Maybe it's a really hard workout, maybe you've had a major trauma or a serious injury from a biking incident, or you've torn a muscle, or maybe you've had surgery and you know your knee has been replaced or your hip has been replaced and your body just really needs to recover. There are several peptides that will specifically go. If you inject them into your body, they will specifically go to the area where your body needs to get repaired. Your body needs to get rejuvenated, your body needs to heal, your body needs to heal and will really help your body to calm down the negative inflammation and to use the positive inflammation to give your body the best possible healing result. One of them is BPC-157, which is Body Protective Compound 157. It is a really amazing peptide that works everywhere in your body. It can actually heal your gut if you have leaky gut syndrome. It can help your muscles, your joints, really repair. If you have arthritis or maybe you've had a joint replacement surgery, it can go right to the target of that inflammation and really calm down that inflammation and help your body repair Kind of amazing.

Speaker 1: 12:02

Tb500 is a similar peptide and they're often used in conjunction and they actually are combined in some of our peptide cocktails together because of the synergy that they have together. It's from thymus and alpha-1, and it plays an amazing role in cellular migration and tissue repair. So not only if you put the two together, you have the anti-inflammatory effects and then you also have this migration of the natural healing properties of your skin, the cells, the cytokines, all of the things that then you're recruited to that area naturally by these peptides, so that not only are you getting the benefit of the peptide but you're stimulating your own body to wake up and start really coming to the area where it needs to focus to really get you healing. Ghkcu is a very cool compound. It's a copper peptide and it actually supports skin rejuvenation. So I'm, of course, absolutely obsessed with GHK-CU because skin is sort of my thing. It helps with wound healing. It helps with the anti-aging processes. Spoiler alert I have a skincare line getting launched in January and one of the peptides that is in my skincare line is GHK-CU, because it helps to reverse all of the damage that we have done over the years to our skin. So there's often compounds or stacks of these peptides that we can put together and, interestingly enough, there is a compound called the Wolverine stack that combines all three of these peptides together.

Speaker 1: 13:45

So if you are undergoing, you know, any kind of process where your body's just not healing well, where you've had injury or you've had chronic stress, or you've had chronic, you've just been, you know, you've just worn your body down and your joints are not responding well. Maybe you have arthritis, maybe you have just this chronic pain or this chronic fatigue, this group of peptides could actually come in and really heal your body from the inside out without any of the side effects of medications and anti-inflammatory drugs that are currently used to treat these things. Because right now a lot of the medications that old school medicine is using to treat inflammatory disorders, like NSAIDs, steroids, are very dangerous long term. They actually break down your tissue and cause continued tissue damage if you use them long term, whereas peptides cause none of that damage and just give you the rejuvenation. So really excited about this particular group of peptides. In my practice for patients that have any kind of inflammatory disease, autoimmune disease, arthritis a lot of the autoimmune diseases, like eczema, psoriasis, alopecia areata, could possibly be targeted and treated without the side effects of a lot of the pharmaceutical drugs with just this category of peptides.

Speaker 1: 15:13

So let's talk about the next category. So the next group of peptides are the growth hormone peptides. These peptides stimulate your body's natural production of growth hormone, and growth hormone is really crucial in metabolism, in tissue repair, in cellular regeneration. But growth hormone production naturally decreases over time. So I'm 52. I have very little natural growth hormone production in my body. So in order to really help build muscle, to really help my body repair and recover from a lot of the stresses I'm putting on it, like the laser procedures and things that I do, I need that natural growth hormone to come in and help me to really repair and enhance my recovery. So there are several peptides that fall in this category that are either growth hormone secretagogues or help your body to increase your natural growth hormone production, your natural growth hormone production. Cgc 1295 enhances the natural growth hormone production in your hypothalamus and that supports fat loss. It supports muscle development and it also improves sleep quality.

Speaker 1: 16:28

How many people out there aren't having trouble sleeping these days? I think all of us. So this is a really great option for those of you that really want to heal and rejuvenate and also get a great night's sleep. Ipamoralin is a great one because it's called the gentle growth hormone secretagogue. It stimulates growth hormone without affecting cortisol, and cortisol is that hormone that's released with stress, or prolactin, which is a hormone that is released when women are lactating. Most of us don't need that to be secreted naturally on a daily basis. So I love epimoralin for people who really want just a boost in their growth hormone without any of the possible side effects any of the possible side effects.

Speaker 1: 17:20

Tesamorelin is a really amazing peptide in this category because it targets visceral fat reduction while supporting overall metabolic health. So if someone's on a GLP-1 and they want, you know, to really target their visceral fat maybe they have a cardiovascular disease and they have a really big abdomen and you know lots of visceral fat this would be a great peptide to add into what they're doing to really help mobilize that visceral fat, while also helping to support their metabolism. So with this group of peptides, we can get enhanced recovery. We can get improved body composition, better sleep quality, increased energy and vitality and also support for tissue healing and regeneration. So, depending on what we're trying to address, this group of hormones really falls into a lot of different categories. So I'll talk to you about how do you know which hormones are right for you at the end of our little discussion today. But this group of hormones is often something that we need to add into someone's regimen if they are really trying to just support their overall metabolism and tissue repair.

Speaker 1: 18:30

So now let's talk about cognitive and neuroprotective peptides. This is sort of a newer category. A lot of people are really, you know, concerned about their long-term cognitive health. We all want to live longer, but we don't want to live longer at the expense of our brains not functioning. No one wants to live longer and be a burden on their family. No one wants to develop dementia. No one wants to develop, you know, some of these neurodegenerative diseases like MS. So are there peptides out there that can maybe prevent these things? And the answer is absolutely there are. So this group of peptides are really specific to supporting brain function, brain health. They actually are able to. Once you inject them into the body, they can cross the blood-brain barrier. A lot of medications can't cross the blood-brain barrier and that's why it's very hard to treat neurodegenerative diseases sometimes, because a lot of the medications that are being formulated out there can't actually get to the source of the problem, which is in the brain. So there are a few here that I want to talk about. The first one is C-Max. It was originally developed in Russia Rush Rusher. It was a visually Okay. It was originally developed in Russia and it actually supports brain circulation. It is neuroprotective and it really supports brain circulation. It is neuroprotective and it really supports cognitive function. So this peptide is actually being used quite a bit in early studies for early onset dementia. So really excited to talk more about this peptide and really excited to do some studies with some of our patients that have early onset dementia to see if we can see some reversal or some improvement with that.

Speaker 1: 20:20

Solanke is known for its anxiolytic or anti-anxiety properties, and the beautiful thing about this is that you can take this peptide and, unlike Valium or a lot of the other medications that we take for preventing anxiety. It doesn't make you sleepy, it doesn't make you groggy, it doesn't slow down your ability to think and be cognitively very, very sharp. So I think Selenic is great for anyone that has anxiety but really is a high performer and wants to continue to stay very active, very sharp, in their career and in their life. So this is a great peptide for anyone who just feels like they have a lot of anxiety, maybe a little brain fog, and they don't want the side effects of the pharmaceutical medications that are available right now. Cerebralicin is a complex peptide mixture that supports brain health and also neuroplasticity, so it actually improves your ability to learn. So this peptide's actually been tested in patients with ADHD because it actually can help patients who have difficulty focusing to really focus and to learn potentially better. So the beautiful thing about this group of peptides is they enhance your focus, your mental clarity, they can help with mood stabilization, they can help with stress, they can help support memory and learning and be very neuroprotective against future brain diseases. So anyone that potentially has a family history of dementia, of MS, of any of the other neurodegenerative diseases, these peptides can actually be protective. And we are looking, we're just at the beginnings, I think, of knowing what these peptides can do. There have not been a lot of controlled clinical trials on most of these peptides, and that is something that new to peptides. Therapeutics and I are partnering together to create these different clinical studies so that we can prove that these peptides really work and potentially are much safer than a lot of the pharmaceutical medications that are out there and hopefully someday we can kind of prevent or reverse or stop all of these neurodegenerative disorders.

Speaker 1: 22:45

So the next one. Let's talk about sexual and hormonal health peptides. This is a group of peptides that help support sexual function and hormone balance. They're great for reproductive health in both men and women. They are recognized to kind of work together with physical, hormonal and a lot of psychological factors together. Bromelanotide, which is PT-141, it works through the nervous system more than the vascular system to support sexual desire and function. So for a lot of patients that you know maybe are having erectile dysfunction or maybe just having decreased libido, this peptide is amazing because it can really just give you that kind of boost that you might need to feel that normal sexual desire that maybe you've been missing since your hormones started to fall away, and a lot of men and women who are now doing bioidentical hormone replacement therapy, this peptide could could be a game changer for those patients. Along with their testosterone or their their bioidentical estrogen and progesterone, this peptide might really just help with their overall sense of well-being, their overall sexual desire and overall sexual improvement.

Speaker 1: 24:04

Cispeptin is another one that plays a really key role in fertility and hormone signaling. So for a lot of my clients that come in and maybe they, maybe they have unexplained fertility. I had unexplained fertility for six years after giving birth to my, my oldest daughter. No matter what I did, I couldn't get pregnant. Even with artificial insemination and one round of in vitro. All of that failed. It took the second round of in vitro for me to get my adorable twins failed. It took the second round of in vitro for me to get my adorable twins. So maybe if I had had Kispeptin back in the day, maybe that would not have been a problem for me, because it really does improve just the natural hormone signaling that can really increase your fertility.

Speaker 1: 24:49

Gonadarylin is another one that supports this hypothalamic pit, pituitary, adrenal, gonadal axis in humans. So, as you probably know, from your brain to your gonads, which is ovaries and testes in men, your whole body communicates together Estrogen, progesterone, testosterone, thyroid cortisol all of these hormones work together, and so gonadarylin is this peptide that just helps all of those hormones work in concert together. So with some of these peptides you can enhance libido and sexual satisfaction. It can support your hormonal balance, also improved mood and relationship, wellness, greater energy and vitality and, of course, reproductive health. So this is a category of peptides that has been very, very minimally studied and we're really excited to see, you know, what these different peptides can do for patients.

Speaker 1: 25:53

The immune modulating peptides are something that I'm super excited about, because there are so many patients that come into me and they just feel like they're chronically inflamed, their joints hurt, they have back pain, they just don't have energy, they just don't feel like themselves anymore. So we know that a certain amount of inflammation is good for your body. If you have a wound or you have an injury, you need a little inflammation to trigger your body to heal it. But sometimes your body doesn't know how to shut off that inflammatory process and that can lead to disorders like osteoarthritis, rheumatoid arthritis. It can lead to all kinds of issues that cause inflammation like maybe even autoimmune disorders like lupus or dermatomyositis. Eczema is an autoimmune disorder. Psoriasis is an autoimmune disorder.

Speaker 1: 26:45

So a lot of times the diseases that are happening in our body are happening because of uncontrolled inflammation and there are peptides that can go in and shut off that switch and say, okay, inflammation, you've done as much as you can do, you've done all the good. Now we need to shut you down and you need to quit causing these inflammatory pathways to keep triggering. Thymus and Alpha-1 is one of those. It helps support your immune function and also cellular immunity. Thymus and Alpha-1 was studied quite a bit during COVID because it actually did help a lot with cellular immunity.

Speaker 1: 27:25

Ll37 is an antimicrobial peptide that supports the body's natural defense mechanisms. So if you are very prone to infections maybe you have an immunologic disorder where you don't make the right amount of immunoglobulins and you have a hard time fighting off infections LL37 could help. Kpv is an ultra-short peptide that has very powerful anti-inflammatory properties. So these peptides, when used in proper amounts and at proper times, can balance your immune response. They can help reduce unwanted inflammation, they can support you if you're having trouble fighting infections, they can enhance your recovery and they can also improve your skin and your gut barrier support. So these peptides can all work together in concert to really give your body this kind of boosting immunity without causing chronic inflammation.

Speaker 1: 28:25

So really exciting what we're looking at here. So what we are really talking about now is trying to figure out what peptides are right for each person. You know there's so many out there and so many of them have very overlapping effects. They're all just really good at, you know, turning the switches in your body that need to be turned to really give you your overall best health and best well-being, really give you your overall best health and best well-being. So we are trying to figure out at NUDA Health and at I'm sorry, let me say we're trying to figure out at NUDA Lab and at Premier, how do we figure out what peptides are best for you that are going to give you the best long-lasting results. Some of the peptides you might need to take daily, some of them you might need to take once a week. Some of them you might need to take once or twice a year. So we have actually created a very short, 10-minute survey. At max Most of us can finish it in about seven minutes.

Speaker 1: 29:29

I know everybody's very busy, but if you go to NoodleLabscom and say, take my Noodavitae, it will give you a little quiz that you can take and it will ask you all kinds of questions about your symptoms, your medical history, the medications you take and based on that it will help you to figure out what peptides are going to be most beneficial for you. And then we can actually sit down and have a consultation to discuss. It may give you two peptides, it may give you five or six peptides that might be beneficial for you. So then we would sit down together, look at your medical history, really determine OK, let's start with maybe one, two, maybe three of these. Let's do this for a few months and see how much improvement we get and then over time we can add peptides in.

Speaker 1: 30:19

We can take peptides away to really target specifically the things that are going on in each individual patient's body. So, unlike somebody that comes in with high cholesterol and I throw you on a statin we're not going to do that this little AI driven quiz will tell us kind of the peptides that are going to work well for you. But then we really customize that to your specific needs and the things that are going to really fit your lifestyle. Some people may not want to do injections every day. Some people may only want to do these every other week, or we can help you determine what is going to work best for your lifestyle, but also give you the results without, hopefully, a lot of the side effects that you may have experienced from trying to treat the disorders that you're dealing with with traditional medicine.

Speaker 1: 31:10

So we're very excited about the possibility of what peptides can do, and we cannot wait to explore this a little bit more with you guys. So, guys, thank you so much for tuning in to an episode of All Things Skin. We sure appreciate you being one of our listeners. Not only do we thank you for listening, but please continue to follow us, give your reviews on any of the podcast platforms that you're listening on, and we can't wait to see you on another episode of All Things Skin.